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Shëndeti

Does coffee help with weight loss?

Does coffee help with weight loss?

We often hear, for example, that coffee reduces appetite and helps with weight loss, while others claim that drinking coffee can lead to an increase in their appetite, i.e. the opposite effect.

Researchers from the Biology Laboratory of the Faculty of Medicine of the Hellenic Academy of Sciences, in collaboration with the GENOSOPHY network and the University of Western Attica, investigated these conflicting views and concluded that drinking 3-4 cups of coffee a day is associated with weight loss , but only in people with a certain genetic background.

Their research, published in the internationally recognized International Journal of Obesity, was based on detailed epidemiological, genetic and experimental data from 300 Greek volunteers.

The volunteers underwent genetic testing with the desire to formulate, with the help of a nutritionist, an individualized nutritional plan based on their genetic profile. They answered questions about their eating habits, appetite and other lifestyle factors from which interesting links were found between coffee consumption, genetic profile and body weight.

The researchers also studied the effect of specific amounts of coffee on the choice of type and amount of food and the secretion of hormones that control appetite, such as asprosin and leptin, in a group of volunteers.

As the responsible person of the study, Aristides Iliopoulos, professor of Biology and Genetics and Director of the Biology Laboratory of the Faculty of Medicine of EKPA, reported for APE-MPE, "the results show us that coffee reduces appetite and can contribute to weight regulation when two 'genetic conditions' are met: having a genetic variant in the CYP1A2 gene that leads to an increase in caffeine metabolism and at the same time a genetic predisposition to obesity.

The research team also found a possible link between coffee and appetite regulation through the hormone asprosin, the levels of which vary depending on the genetic profile of coffee metabolism.

"The results of the study show us that 3-4 cups of coffee can be included in weight management diets in individuals with an increased predisposition to obesity and a genetic profile of high caffeine metabolism," said Dr. Calliope Guscou, first author. of the article.

The researchers intend to further study the types of coffee and their components that have the optimal effect on health. This study also paves the way for scientists to identify molecular mechanisms for treating obesity, which has reached epidemic proportions in recent years.